BDBM50119807 1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyclo[11.2.1.02,12.04,9]hexadeca-4(9),5,7-trien-10-ylcarbonyl]phenyl}-2-(4-methylphenyl)benzamide::CHEMBL430841

SMILES Cc1ccc(cc1)-c1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1C[C@@H]2C3CCC(C3)N2Cc2cc(Cl)ccc12

InChI Key InChIKey=AGTYAPDOOSGWIN-ZTFYXODMSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119807   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  13nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V2 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataKi:  23nMAssay Description:Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-Arg-vasopressin binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50119807(1N-{4-[6-chloro-16-methyl-(12S)-2,10-diazatetracyc...)
Affinity DataIC50:  24nMAssay Description:Inhibition of [3H]-Arg-vasopressin binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed