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BDBM50120555 CHEMBL113145::Dibutyl-{3-[4-(5,7-dimethyl-imidazo[1,2-a]pyridin-2-yl)-phenoxy]-propyl}-amine

SMILES: CCCCN(CCCC)CCCOc1ccc(cc1)-c1cn2c(C)cc(C)cc2n1

InChI Key: InChIKey=BGFLLXIGKYNRPQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120555   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50120555
PNG
(CHEMBL113145 | Dibutyl-{3-[4-(5,7-dimethyl-imidazo...)
Show SMILES CCCCN(CCCC)CCCOc1ccc(cc1)-c1cn2c(C)cc(C)cc2n1
Show InChI InChI=1S/C26H37N3O/c1-5-7-14-28(15-8-6-2)16-9-17-30-24-12-10-23(11-13-24)25-20-29-22(4)18-21(3)19-26(29)27-25/h10-13,18-20H,5-9,14-17H2,1-4H3
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PC cid
PC sid
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Similars

Article
PubMed
2.00E+3n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for human histamine H3 receptor


Bioorg Med Chem Lett 12: 3309-12 (2002)


Article DOI: 10.1016/s0960-894x(02)00738-2
BindingDB Entry DOI: 10.7270/Q2KH0MPG
More data for this
Ligand-Target Pair