BDBM50121030 CHEMBL115734::[(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-propyl]-carbamic acid benzyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@@H]2OCCN2C1=O)OCc1ccccc1

InChI Key InChIKey=VYRSXJDNPISAMG-UEXGIBASSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121030   

TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121030(CHEMBL115734 | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-b...)
Affinity DataIC50:  77nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121030(CHEMBL115734 | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-b...)
Affinity DataIC50:  1.22E+4nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin B cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121030(CHEMBL115734 | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-b...)
Affinity DataIC50:  5nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin K cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121030(CHEMBL115734 | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-b...)
Affinity DataIC50:  4nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin L cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed