BDBM50121036 CHEMBL421054::[(S)-1-((R)-7-Oxo-4-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-(S)-phenyl-ethyl]-carbamic acid benzyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@@H]2SCCN2C1=O)OCc1ccccc1

InChI Key InChIKey=MKBBOQYCGLQYLG-UEXGIBASSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50121036   

TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121036(CHEMBL421054 | [(S)-1-((R)-7-Oxo-4-thia-1-aza-bicy...)
Affinity DataIC50:  6.68E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121036(CHEMBL421054 | [(S)-1-((R)-7-Oxo-4-thia-1-aza-bicy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121036(CHEMBL421054 | [(S)-1-((R)-7-Oxo-4-thia-1-aza-bicy...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed