BDBM50121906 CHEMBL31363::[(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester

SMILES CC(C)CO[C@@H]1NC(=O)[C@H]1NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=VGKJNJDNQCLECA-MZKRTTBSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121906   

TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121906(CHEMBL31363 | [(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-az...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121906(CHEMBL31363 | [(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-az...)
Affinity DataIC50:  91nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121906(CHEMBL31363 | [(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-az...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121906(CHEMBL31363 | [(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-az...)
Affinity DataIC50:  6.46E+3nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121906(CHEMBL31363 | [(S)-1-((2S,3S)-2-Isobutoxy-4-oxo-az...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed