BDBM50121911 Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester::CHEMBL285585

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@@H](NC1=O)OC(=O)c1ccccc1)OCc1ccccc1

InChI Key InChIKey=HFXHAUDVMVAJNA-FBLLAGFSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121911   

TargetNeutrophil elastase(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121911(Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121911(Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylami...)
Affinity DataIC50:  2.75E+4nMAssay Description:Inhibition of recombinant rat Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121911(Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylami...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121911(Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylami...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121911(Benzoic acid (2S,3S)-3-((S)-2-benzyloxycarbonylami...)
Affinity DataIC50:  166nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed