BDBM50122274 CHEMBL3617618

SMILES C[C@@H]1CN(C(=O)c2cc(COc3ccc(F)cn3)nn12)c1cccc(C)c1

InChI Key InChIKey=FKKBESIUKQKYJF-CQSZACIVSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122274   

TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50122274(CHEMBL3617618)
Affinity DataIC50:  214nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50122274(CHEMBL3617618)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50122274(CHEMBL3617618)
Affinity DataIC50:  216nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50122274(CHEMBL3617618)
Affinity DataEC50: <1.00E+4nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed