BDBM50122333 (S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy]-phenyl}-2-ethoxy-propionic acid::CHEMBL89152

SMILES CCO[C@@H](Cc1ccc(OC\C=C(/c2ccccc2)c2ccc(Br)cc2)cc1)C(O)=O

InChI Key InChIKey=CJGRPCBFIYJMOR-WWNGRIQCSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50122333   

LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  1.10E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  1.50E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  1.10E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  1.50E+3nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  4.27E+3nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  900nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor delta (PPAR delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  1.10E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  2.19E+3nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50122333((S)-3-{4-[(E)-3-(4-Bromo-phenyl)-3-phenyl-allyloxy...)
Affinity DataEC50:  1.50E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed