BDBM50122503 1-{1-(4-fluorophenyl)-2-[4-(3-phenylpropyl)hexahydro-1-pyrazinyl]ethyl}-4-methylhexahydropyrazine::CHEMBL12615

SMILES CN1CCN(CC1)C(CN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=GBSPIAIWKOVXMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122503   

TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122503(1-{1-(4-fluorophenyl)-2-[4-(3-phenylpropyl)hexahyd...)
Affinity DataIC50: 3.83E+3nMAssay Description:In vitro ability to inhibit the binding of alpha [125I]NDP-MSH to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50122503(1-{1-(4-fluorophenyl)-2-[4-(3-phenylpropyl)hexahyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro ability to inhibit the binding of [125I]AGRP to the human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed