BDBM50122872 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide::CHEMBL117287::PRUCALOPRIDE::US9663465, prucalopride

SMILES: COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12

InChI Key: InChIKey=ZPMNHBXQOOVQJL-UHFFFAOYSA-N

Data: 60 KI  1 Kd  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 66 hits for monomerid = 50122872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Rat)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Rat)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		44.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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AP-4 complex subunit sigma-1 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Mouse)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vasoactive intestinal polypeptide receptor 1 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Norepinephrine transporter (Rat)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin (Guinea pig)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Guinea pig)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-arrestin-1 (Rabbit)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 10 subunit alpha (Rat)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Thromboxane A2 receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neuromedin-K receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1F (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1E (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 5A (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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B2 bradykinin receptor (Human)	BDBM50122872 (4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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