BDBM50123052 2-[4-(3-{8-azaspiro[bicyclo[3.2.1]octane-3,2'-oxolane]-8-ylsulfonyl}-4-hydroxyphenoxy)-3,5-dichlorophenyl]-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione::2-{3,5-dichloro-4-[4-hydroxy-3-spiro[8-azabicyclo[3.2.1]octane-3,2'-(tetrahydrofuran)]-8-ylsulfonylphenoxy]phenyl}-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione::CHEMBL125946
SMILES Oc1ccc(Oc2c(Cl)cc(cc2Cl)-n2ncc(=O)[nH]c2=O)cc1S(=O)(=O)N1C2CCC1CC1(CCCO1)C2
InChI Key InChIKey=JHJHCOACTCIKNP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50123052
Affinity DataKi: 0.280nMAssay Description:Inhibitory activity against [125I]T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.776nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Effective concentration of the compound binding towards TRbeta1 in E25B2 cells (agonistic activity)More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Effective concentration of the compound binding towards TRalpha in E25B2 cells (agonistic activity)More data for this Ligand-Target Pair