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BDBM50123117 6,7-Dihydroxy-2-[1-(2-trifluoromethyl-phenyl)-meth-(E)-ylidene]-benzofuran-3-one::CHEMBL335644

SMILES: Oc1ccc2C(=O)\C(Oc2c1O)=C/c1ccccc1C(F)(F)F

InChI Key: InChIKey=QAPLXVYEMYDNIJ-KPKJPENVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123117   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chorismate synthase


(Streptococcus pneumoniae)
BDBM50123117
PNG
(6,7-Dihydroxy-2-[1-(2-trifluoromethyl-phenyl)-meth...)
Show SMILES Oc1ccc2C(=O)\C(Oc2c1O)=C/c1ccccc1C(F)(F)F
Show InChI InChI=1S/C16H9F3O4/c17-16(18,19)10-4-2-1-3-8(10)7-12-13(21)9-5-6-11(20)14(22)15(9)23-12/h1-7,20,22H/b12-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.73E+4n/an/an/an/an/an/a



PanTherix Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Streptococcus pneumoniae chorismate synthase


Bioorg Med Chem Lett 13: 423-6 (2003)


Article DOI: 10.1016/s0960-894x(02)00957-5
BindingDB Entry DOI: 10.7270/Q2TH8M2M
More data for this
Ligand-Target Pair