BDBM50123274 6-amino(imino)methylamino-19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol; ditrifluoracetic acid::CHEMBL348011
SMILES [#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8]
InChI Key InChIKey=FZJHXKMITTVIBA-DVNJHFJZSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50123274
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity for kappa opioid receptor was measured using [3H]U-69593More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for Mu-recepto...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Binding affinity to delta opioid receptor was measured using [3H]DADLEMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding affinity to mu opioid receptor was measured using [3H]DAMGOMore data for this Ligand-Target Pair