BDBM50123274 6-amino(imino)methylamino-19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol; ditrifluoracetic acid::CHEMBL348011

SMILES [#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8]

InChI Key InChIKey=FZJHXKMITTVIBA-DVNJHFJZSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50123274   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123274(6-amino(imino)methylamino-19-cyclopropylmethyl-11-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for kappa opioid receptor was measured using [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123274(6-amino(imino)methylamino-19-cyclopropylmethyl-11-...)
Affinity DataKi:  1nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123274(6-amino(imino)methylamino-19-cyclopropylmethyl-11-...)
Affinity DataKi:  6.10nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for Mu-recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123274(6-amino(imino)methylamino-19-cyclopropylmethyl-11-...)
Affinity DataKi:  6.5nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123274(6-amino(imino)methylamino-19-cyclopropylmethyl-11-...)
Affinity DataKi:  19nMAssay Description:Binding affinity to delta opioid receptor was measured using [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123274(6-amino(imino)methylamino-19-cyclopropylmethyl-11-...)
Affinity DataKi:  26nMAssay Description:Binding affinity to mu opioid receptor was measured using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed