BDBM50123286 5-(1H-Indol-3-ylmethylene)-2-thioxo-1,3-di-o-tolyl-dihydro-pyrimidine-4,6-dione::CHEMBL347715

SMILES Cc1ccccc1N1C(=S)N(C(=O)C(=Cc2c[nH]c3ccccc23)C1=O)c1ccccc1C

InChI Key InChIKey=YIJCAGLGSVDTMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123286   

TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123286(5-(1H-Indol-3-ylmethylene)-2-thioxo-1,3-di-o-tolyl...)
Affinity DataIC50:  790nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed