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BDBM50123575 (3-{4-[3-(Bis-cyclopropylmethyl-amino)-propyl]-piperazin-1-yl}-propyl)-(7-chloro-quinolin-4-yl)-amine::CHEMBL153507::N-(3-(4-(3-(bis(cyclopropylmethyl)amino)propyl)piperazin-1-yl)propyl)-7-chloroquinolin-4-amine

SMILES: Clc1ccc2c(NCCCN3CCN(CCCN(CC4CC4)CC4CC4)CC3)ccnc2c1

InChI Key: InChIKey=NJVDETRDEAELLF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123575   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histidine-rich protein


(Plasmodium falciparum)
BDBM50123575
PNG
((3-{4-[3-(Bis-cyclopropylmethyl-amino)-propyl]-pip...)
Show SMILES Clc1ccc2c(NCCCN3CCN(CCCN(CC4CC4)CC4CC4)CC3)ccnc2c1
Show InChI InChI=1S/C27H40ClN5/c28-24-7-8-25-26(9-11-30-27(25)19-24)29-10-1-12-31-15-17-32(18-16-31)13-2-14-33(20-22-3-4-22)21-23-5-6-23/h7-9,11,19,22-23H,1-6,10,12-18,20-21H2,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27.1n/an/an/an/an/an/a



Universit£ de Lille II

Curated by ChEMBL


Assay Description
In vitro inhibition of beta-hematin formation


J Med Chem 46: 542-57 (2003)


Article DOI: 10.1021/jm020960r
BindingDB Entry DOI: 10.7270/Q27W6DDC
More data for this
Ligand-Target Pair