BindingDB logo
myBDB logout

BDBM50123625 (S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalene-1,2-diol::CHEMBL155613

SMILES: CCCN(CCc1cccs1)[C@H]1CCc2c(C1)ccc(O)c2O

InChI Key: InChIKey=NRLVAYFPZFCJHQ-HNNXBMFYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DRD2


(BOVINE)
BDBM50123625
PNG
((S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7...)
Show SMILES CCCN(CCc1cccs1)[C@H]1CCc2c(C1)ccc(O)c2O
Show InChI InChI=1S/C19H25NO2S/c1-2-10-20(11-9-16-4-3-12-23-16)15-6-7-17-14(13-15)5-8-18(21)19(17)22/h3-5,8,12,15,21-22H,2,6-7,9-11,13H2,1H3/t15-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6n/an/an/an/an/an/an/an/a



University Centre for Pharmacy

Curated by ChEMBL


Assay Description
Binding affinity of compound for Dopamine receptor D2 using [3H]-N-0437


J Med Chem 46: 584-90 (2003)


Article DOI: 10.1021/jm020990u
BindingDB Entry DOI: 10.7270/Q2H41QS1
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50123625
PNG
((S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7...)
Show SMILES CCCN(CCc1cccs1)[C@H]1CCc2c(C1)ccc(O)c2O
Show InChI InChI=1S/C19H25NO2S/c1-2-10-20(11-9-16-4-3-12-23-16)15-6-7-17-14(13-15)5-8-18(21)19(17)22/h3-5,8,12,15,21-22H,2,6-7,9-11,13H2,1H3/t15-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
110n/an/an/an/an/an/an/an/a



University Centre for Pharmacy

Curated by ChEMBL


Assay Description
Binding affinity of compound for Dopamine receptor D1 using [3H]-SCH- 23390


J Med Chem 46: 584-90 (2003)


Article DOI: 10.1021/jm020990u
BindingDB Entry DOI: 10.7270/Q2H41QS1
More data for this
Ligand-Target Pair