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BDBM50123701 1-(2-Hydroxy-phenyl)-5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-pentan-1-one::CHEMBL157081

SMILES: COc1ccccc1N1CCN(CCCCC(=O)c2ccccc2O)CC1

InChI Key: InChIKey=GWSVWAFZLGWAGM-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123701   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50123701
PNG
(1-(2-Hydroxy-phenyl)-5-[4-(2-methoxy-phenyl)-piper...)
Show SMILES COc1ccccc1N1CCN(CCCCC(=O)c2ccccc2O)CC1
Show InChI InChI=1S/C22H28N2O3/c1-27-22-12-5-3-9-19(22)24-16-14-23(15-17-24)13-7-6-11-21(26)18-8-2-4-10-20(18)25/h2-5,8-10,12,25H,6-7,11,13-17H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.10n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Binding affinity to the rat 5-hydroxytryptamine 1A receptor


J Med Chem 46: 646-9 (2003)


Article DOI: 10.1021/jm020994z
BindingDB Entry DOI: 10.7270/Q23T9GKN
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50123701
PNG
(1-(2-Hydroxy-phenyl)-5-[4-(2-methoxy-phenyl)-piper...)
Show SMILES COc1ccccc1N1CCN(CCCCC(=O)c2ccccc2O)CC1
Show InChI InChI=1S/C22H28N2O3/c1-27-22-12-5-3-9-19(22)24-16-14-23(15-17-24)13-7-6-11-21(26)18-8-2-4-10-20(18)25/h2-5,8-10,12,25H,6-7,11,13-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16.4n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Binding affinity to the rat 5-hydroxytryptamine 7 receptor


J Med Chem 46: 646-9 (2003)


Article DOI: 10.1021/jm020994z
BindingDB Entry DOI: 10.7270/Q23T9GKN
More data for this
Ligand-Target Pair