BDBM50123755 2-{(R)-2-[1-((S)-(S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidin-1-yl}-2-oxo-1-((S)-phenylmethyl)-ethyl-ammonium

SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@@H]([NH3+])Cc1ccccc1

InChI Key InChIKey=RYHITPRHAAWYLY-UHFFFAOYSA-O

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123755   

TargetMu-type opioid receptor(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123755(2-{(R)-2-[1-((S)-(S)-1-Carbamoyl-2-phenyl-ethylcar...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123755(2-{(R)-2-[1-((S)-(S)-1-Carbamoyl-2-phenyl-ethylcar...)
Affinity DataEC50:  31nMAssay Description:Compound tested at 10 uM for the ability to induce Opioid receptor mu 1-mediated binding of [35S]GTP-gamma-S to G proteins in CHO membrane preparatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123755(2-{(R)-2-[1-((S)-(S)-1-Carbamoyl-2-phenyl-ethylcar...)
Affinity DataKi:  1.04E+4nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123755(2-{(R)-2-[1-((S)-(S)-1-Carbamoyl-2-phenyl-ethylcar...)
Affinity DataKi:  2.50E+4nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed