BDBM50124303 3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyethyl)-4,19-di(4-hydroxybenzyl)-7-isobutyl-28-isopropyl-22-(2-methylsulfanylethyl)-3,6,9,12,18,21,24,27,30,33-decaoxo-14-thia-2,5,8,11,17,20,23,26,29,32-decaazacyclotritriacontanyl]propanoic acid::CHEMBL444114::cyclo(CH2CO-Glu1-Leu2-Tyr3-Glu4-Asn5-Val6-Gly7-Met8-Tyr9-Cys10)-amide

SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C

InChI Key InChIKey=BZLRZJFFHMIABH-AGEHIQCHSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124303   

TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50124303(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against Growth factor receptor bound protein 2 using ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50124303(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50124303(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity against Growth factor receptor bound protein 2 using ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50124303(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)
Affinity DataIC50:  1.50E+4nMAssay Description:Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50124303(3-[16-carbamoyl-31-carbamoylmethyl-10-(2-carboxyet...)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to GST-tagged recombinant Grb2 SH2 domain by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed