BDBM50124525 4'-amino-5'-fluorospiro[hexahydropyridine-4,2'-(1',2'-dihydroquinazoline)]-1-yl-3-thienylmethanone::5'-fluoro-1-(thien-3-ylcarbonyl)-1'H-spiro[piperidine-4,2'-quinazolin]-4'-amine::CHEMBL170580

SMILES NC1=NC2(CCN(CC2)C(=O)c2ccsc2)Nc2cccc(F)c12

InChI Key InChIKey=FHRCQQIVIJAXMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124525   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50124525(4'-amino-5'-fluorospiro[hexahydropyridine-4,2'-(1'...)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50124525(4'-amino-5'-fluorospiro[hexahydropyridine-4,2'-(1'...)
Affinity DataIC50:  67nMAssay Description:Inhibition of iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50124525(4'-amino-5'-fluorospiro[hexahydropyridine-4,2'-(1'...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibitory activity against human neuronal nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed