BDBM50124935 2-Methyl-5-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one::CHEMBL345438

SMILES CC1Cc2cccc3CCC(N4CCN(Cc5ccc(C)cc5)CC4)C(=O)N1c23

InChI Key InChIKey=DKBPJHJAUABOCD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124935   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50124935(2-Methyl-5-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-YM 09151 from D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50124935(2-Methyl-5-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-YM 09151 from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50124935(2-Methyl-5-[4-(4-methyl-benzyl)-piperazin-1-yl]-1,...)
Affinity DataKi:  1.00E+3nMAssay Description:D4 receptor functional activity was measured inhibition of quinpirole stimulated [35S]-GTP-gammaS binding from cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed