BDBM50125052 CHEMBL3623004::US10130617, Example 1::US20240043442, Example AZD9496::US20240131013, Compound AZD-9496::WO-2014/191726, Example 1

SMILES: C[C@@H]1Cc2c3ccccc3[nH]c2[C@H](N1CC(C)(C)F)c4c(cc(cc4F)/C=C/C(=O)O)F

InChI Key: InChIKey=DFBDRVGWBHBJNR-UHFFFAOYSA-N

Data: 25 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50125052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.209	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.138	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.282	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a	n/a
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Steroid hormone receptor ERR1 (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.372	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.372	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.372	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50125052 (CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair