BDBM50125265 CHEMBL204021::N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulfanyl)-4-oxo-4,5,6,7-tetrahydro-cyclopentapyrimidin-1-yl]-N-(4'-trifluoromethyl-biphenyl-4-ylmethyl)-acetamide

SMILES: CCN(CC)CCN(Cc1ccc(cc1)-c1ccc(cc1)C(F)(F)F)C(=O)Cn1c2CCCc2c(=O)nc1SCc1ccc(F)cc1

InChI Key: InChIKey=WDPFJWLDPVQCAJ-UHFFFAOYSA-N

Data: 1 KI  17 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50125265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0631	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0350	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0490	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0490	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	49.7	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0490	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Human)	BDBM50125265 (N-(2-Diethylamino-ethyl)-2-[2-(4-fluoro-benzylsulf...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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