BDBM50125652 (S)-4-Methyl-2-(4-methyl-pentanoylamino)-pentanoic acid ((1S,2R)-1-cyclohexylmethyl-2-hydroxy-3-oxo-3-phenyl-propyl)-amide::CHEMBL18705

SMILES CC(C)CCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(O)c1ccccc1

InChI Key InChIKey=RSDVKJAQECKPEU-OKHNBNEASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125652   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125652((S)-4-Methyl-2-(4-methyl-pentanoylamino)-pentanoic...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of amyloid beta protein production in transfected H4 (neuroglioma) cells expressing APF constructs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed