BDBM50125652 (S)-4-Methyl-2-(4-methyl-pentanoylamino)-pentanoic acid ((1S,2R)-1-cyclohexylmethyl-2-hydroxy-3-oxo-3-phenyl-propyl)-amide::CHEMBL18705
SMILES CC(C)CCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(O)c1ccccc1
InChI Key InChIKey=RSDVKJAQECKPEU-OKHNBNEASA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50125652
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of amyloid beta protein production in transfected H4 (neuroglioma) cells expressing APF constructs.More data for this Ligand-Target Pair