BDBM50125910 1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea::CHEMBL22113

SMILES COc1ccc(NC(=O)Nc2nc3nn(C)c(SC)c3c3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=GJFVCSIWUJNFMJ-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50125910   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125910(1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyraz...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]- SCH-58261 binding at human Adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125910(1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyraz...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]- DPCPX from human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125910(1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyraz...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]- DPCPX binding at human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125910(1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyraz...)
Affinity DataKi:  212nMAssay Description:Displacement of [3H]- MRE 308F20 binding from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125910(1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyraz...)
Affinity DataIC50:  813nMAssay Description:Antagonist activity as inhibition of cAMP generation after agonist-modulation of Adenosine A3 receptor with 100 nM CI-IB-MECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125910(1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyraz...)
Affinity DataIC50:  17.5nMAssay Description:Antagonist activity as inhibition of cAMP generation after agonist-modulation of human Adenosine A2A receptor with 100 nM NECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed