BDBM50125935 (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester::(R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylicacid ethyl ester::3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ethyl ester::Amidate::CHEMBL681::Etomidate::R(+)-etomidate::R-ETOMIDATE

SMILES: CCOC(=O)c1cncn1[C@H](C)c2ccccc2

InChI Key: InChIKey=NPUKDXXFDDZOKR-UHFFFAOYSA-N

Data: 12 IC50  5 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50125935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a
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Cytochrome P450 11B1, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B2, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B1, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B2, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
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Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
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Acetylcholine receptor subunit alpha/beta/delta/gamma (Pacific electric ray)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholine receptor subunit alpha/beta/delta/gamma (Mouse)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Human)	BDBM50125935 (CHEMBL681 | R(+)-etomidate | Amidate | (R)-1-(1-ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair