BDBM50125939 3-((S)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid 2-(3-methyl-3H-diazirin-3-yl)-ethyl ester::CHEMBL22676

SMILES C[C@@H](c1ccccc1)n1cncc1C(=O)OCCC1(C)N=N1

InChI Key InChIKey=DUOHNSBKYJHAMQ-LBPRGKRZSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50125939   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50125939(3-((S)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic a...)
Affinity DataIC50:  6.63E+4nMAssay Description:In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50125939(3-((S)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic a...)
Affinity DataEC50:  2.00E+4nMAssay Description:Enhancement of currents elicited by GABA at EC5 (6-12 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed