BDBM50126062 (3-{2-[(R)-2-((S)-3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yloxy)-acetic acid::CHEMBL24350

SMILES C[C@@H](Cc1c[nH]c2c(OCC(O)=O)cccc12)NC[C@H](O)c1cccc(Cl)c1

InChI Key InChIKey=FHEYFIGWYQJVDR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126062   

TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126062((3-{2-[(R)-2-((S)-3-Chloro-phenyl)-2-hydroxy-ethyl...)
Affinity DataEC50:  1.20nMAssay Description:Agonistic activity against human Beta-3 adrenergic receptor as cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126062((3-{2-[(R)-2-((S)-3-Chloro-phenyl)-2-hydroxy-ethyl...)
Affinity DataEC50:  10nMAssay Description:Agonistic activity against human Beta-3 adrenergic receptor as cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50126062((3-{2-[(R)-2-((S)-3-Chloro-phenyl)-2-hydroxy-ethyl...)
Affinity DataEC50:  14nMAssay Description:Agonistic activity against human Beta-1 adrenergic receptor by measuring cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed