BDBM50126115 CHEMBL3627744

SMILES OC(=O)[C@H](CCCn1cc(nn1)-c1ccc(cc1)C(F)(F)F)NC(=O)OCC1c2ccccc2-c2ccccc12

InChI Key InChIKey=OEFVQIUYYWZFFZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126115   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50126115(CHEMBL3627744)
Affinity DataKi:  6.96E+3nMAssay Description:Inhibition of human MDM2 (17 to 125 residues) assessed as apparent inhibition constant for reduction in MDM2 interaction with FAM-LTFEHYWAQLTS-CONH2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50126115(CHEMBL3627744)
Affinity DataIC50: 4.98E+4nMAssay Description:Inhibition of human MDM2 (17 to 125 residues) assessed as reduction in MDM2 interaction with FAM-LTFEHYWAQLTS-CONH2 peptide incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed