BDBM50127751 CHEMBL3629704

SMILES Cc1cc(cc2cn[nH]c12)C(=O)N1CC2(C1)CCN(CC2)C(=O)OC(C)(C)C

InChI Key InChIKey=BLXPQTMNYUXYSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127751   

TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127751(CHEMBL3629704)
Affinity DataIC50:  810nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127751(CHEMBL3629704)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed