BDBM50128400 2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,2,3,4-tetrahydro-quinolin-6-ol::CHEMBL60538

SMILES Oc1ccc2N(Cc3ccc(OCCN4CCCCC4)cc3)C(CCc2c1)c1ccccc1

InChI Key InChIKey=OQJYJENHHOZHPV-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128400   

TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128400(2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128400(2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,...)
Affinity DataKi:  4nMAssay Description:Binding affinity for estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128400(2-Phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1,...)
Affinity DataIC50:  490nMAssay Description:Inhibition of estradiol-stimulated MCF-7 breast adenocarcinoma cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed