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BDBM50129014 CHEMBL3629223

SMILES: CC(C(=O)NCc1ccc(cc1SCc1ccco1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=SGEDUZSJFQPDGW-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129014   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50129014
PNG
(CHEMBL3629223)
Show SMILES CC(C(=O)NCc1ccc(cc1SCc1ccco1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1/C23H22F4N2O4S2/c1-14(15-6-8-20(19(24)10-15)29-35(2,31)32)22(30)28-12-16-5-7-17(23(25,26)27)11-21(16)34-13-18-4-3-9-33-18/h3-11,14,29H,12-13H2,1-2H3,(H,28,30)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
3.20n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay


Bioorg Med Chem 23: 6844-54 (2015)


Article DOI: 10.1016/j.bmc.2015.10.001
BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair