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BDBM50129111 (2-Chloro-5-methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-oxazol-2-yl)-amine::CHEMBL62944

SMILES: COc1cc(Nc2ncc(o2)-c2ccccc2)c(Cl)cc1-c1cnco1

InChI Key: InChIKey=LCQVSLKHQHPSGL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129111   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50129111
PNG
((2-Chloro-5-methoxy-4-oxazol-5-yl-phenyl)-(5-pheny...)
Show SMILES COc1cc(Nc2ncc(o2)-c2ccccc2)c(Cl)cc1-c1cnco1
Show InChI InChI=1S/C19H14ClN3O3/c1-24-16-8-15(14(20)7-13(16)18-9-21-11-25-18)23-19-22-10-17(26-19)12-5-3-2-4-6-12/h2-11H,1H3,(H,22,23)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.60E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 13: 2059-63 (2003)


Article DOI: 10.1016/s0960-894x(03)00258-0
BindingDB Entry DOI: 10.7270/Q22Z14X1
More data for this
Ligand-Target Pair