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BDBM50129792 2-(4-Dimethylamino-phenyl)-benzothiazol-6-ol::CHEMBL91449

SMILES: CN(C)c1ccc(cc1)-c1nc2ccc(O)cc2s1

InChI Key: InChIKey=WDXCWXZECJHKRF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129792   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta amyloid A4 protein


(Homo sapiens (human))
BDBM50129792
PNG
(2-(4-Dimethylamino-phenyl)-benzothiazol-6-ol | CHE...)
Show SMILES CN(C)c1ccc(cc1)-c1nc2ccc(O)cc2s1
Show InChI InChI=1S/C15H14N2OS/c1-17(2)11-5-3-10(4-6-11)15-16-13-8-7-12(18)9-14(13)19-15/h3-9,18H,1-2H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
4.40n/an/an/an/an/an/an/an/a



University of Pittsburgh

Curated by ChEMBL


Assay Description
Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.


J Med Chem 46: 2740-54 (2003)

More data for this
Ligand-Target Pair