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BDBM50129794 CHEMBL328660::[4-(6-Bromo-benzothiazol-2-yl)-phenyl]-methyl-amine

SMILES: CNc1ccc(cc1)-c1nc2ccc(Br)cc2s1

InChI Key: InChIKey=LXLPEJYMUUWZGT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129794   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta amyloid A4 protein


(Homo sapiens (human))
BDBM50129794
PNG
(CHEMBL328660 | [4-(6-Bromo-benzothiazol-2-yl)-phen...)
Show SMILES CNc1ccc(cc1)-c1nc2ccc(Br)cc2s1
Show InChI InChI=1S/C14H11BrN2S/c1-16-11-5-2-9(3-6-11)14-17-12-7-4-10(15)8-13(12)18-14/h2-8,16H,1H3
PDB
MMDB

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Similars

Article
PubMed
1.70n/an/an/an/an/an/an/an/a



University of Pittsburgh

Curated by ChEMBL


Assay Description
Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.


J Med Chem 46: 2740-54 (2003)

More data for this
Ligand-Target Pair