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BDBM50129895 1-(2-Cyclohexyl-2-cyclohexylamino-acetyl)-pyrrolidine-2-carbonitrile::CHEMBL330623

SMILES: O=C([C@@H](NC1CCCCC1)C1CCCCC1)N1CCC[C@H]1C#N

InChI Key: InChIKey=AKYYKUMHHVQQLE-ROUUACIJSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129895   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50129895
PNG
(1-(2-Cyclohexyl-2-cyclohexylamino-acetyl)-pyrrolid...)
Show SMILES O=C([C@@H](NC1CCCCC1)C1CCCCC1)N1CCC[C@H]1C#N
Show InChI InChI=1S/C19H31N3O/c20-14-17-12-7-13-22(17)19(23)18(15-8-3-1-4-9-15)21-16-10-5-2-6-11-16/h15-18,21H,1-13H2/t17-,18-/m0/s1
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.86E+4n/an/an/an/an/an/a



Novartis Institute for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cells


J Med Chem 46: 2774-89 (2003)


Article DOI: 10.1021/jm030091l
BindingDB Entry DOI: 10.7270/Q20001HR
More data for this
Ligand-Target Pair