BDBM50129980 3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-prop-1-ynyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl]-methyl-amino}-propyl)-tetrahydro-pyran-2-carboxylic acid::CHEMBL78124

SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)CCCC1OC(C(O)C(O)C1O)C(O)=O

InChI Key InChIKey=SXSJBHOSJGHDBE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129980   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50129980(3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Dexamethasone binding to Glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50129980(3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17...)
Affinity DataIC50: 550nMAssay Description:Inhibition of Dexamethasone stimulated transcriptional activity in CHO cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50129980(3,4,5-Trihydroxy-6-(3-{[4-((8S,11R,13S,14S,17S)-17...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of prednisilone-induced tyrosine aminotransferase (TAT) activity in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed