BDBM50130198 CHEMBL3629653

SMILES: [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)NC(=O)[C@H](Cc1ccccc1)N1C(=O)N[C@@H](Cc2ccc(Br)cc2)C1=O

InChI Key: InChIKey=SKJJNSZIXFNENI-UNMCSNQZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50130198 (CHEMBL3629653) Show SMILES [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)NC(=O)[C@H](Cc1ccccc1)N1C(=O)N[C@@H](Cc2ccc(Br)cc2)C1=O Show InChI InChI=1S/C25H20BrClN4O7S/c26-17-8-6-16(7-9-17)12-20-24(33)30(25(34)28-20)22(13-15-4-2-1-3-5-15)23(32)29-39(37,38)18-10-11-19(27)21(14-18)31(35)36/h1-11,14,20,22H,12-13H2,(H,28,34)(H,29,32)/t20-,22-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Competitive binding affinity to Bcl-2 (unknown origin) preincubated for 30 mins followed by 5-FAM-Bid-BH3 peptide addition measured after 20 mins by ...				Bioorg Med Chem 23: 7359-65 (2015) Article DOI: 10.1016/j.bmc.2015.10.023 BindingDB Entry DOI: 10.7270/Q2FQ9ZD8
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