BDBM50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine

SMILES: OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1

InChI Key: InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N

Data: 44 KI  24 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 68 hits for monomerid = 50130273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldehyde oxidase 1 (Mouse)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase 1A1 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	524	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase 1 (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase 1 (Crab-eating macaque)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
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Ubiquitin-conjugating enzyme E2 N (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
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Cytochrome P450 1A2 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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NADPH oxidase 1 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ubiquitin-conjugating enzyme E2 N (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-related protein A1 (Mouse)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		5.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histamine H1 receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		8.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Guinea pig)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 7 (Human)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50130273 (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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