BDBM50130326 2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl]carbonyl}-N-methylhydrazinecarbothioamide::CHEMBL323554

SMILES: C\N=C(/S)NNC(=O)c1cccn(Cc2cccc(Cl)c2)c1=O

InChI Key: InChIKey=OHLBEDKVGBHTLP-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50130326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50130326 (2-{[1-(3-chlorobenzyl)-2-oxo-1,2-dihydropyridin-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair