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BDBM50130459 CHEMBL321343::N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-2-nitro-benzamide

SMILES: CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3[N+]([O-])=O)nc12

InChI Key: InChIKey=FXZBOGLCSOPCIH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130459   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130459
PNG
(CHEMBL321343 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3[N+]([O-])=O)nc12
Show InChI InChI=1S/C20H21N5O3/c1-24-10-8-13(9-11-24)15-12-21-16-6-7-18(22-19(15)16)23-20(26)14-4-2-3-5-17(14)25(27)28/h2-7,12-13,21H,8-11H2,1H3,(H,22,23,26)
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PC sid
UniChem

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Similars

Article
PubMed
19n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50130459
PNG
(CHEMBL321343 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3[N+]([O-])=O)nc12
Show InChI InChI=1S/C20H21N5O3/c1-24-10-8-13(9-11-24)15-12-21-16-6-7-18(22-19(15)16)23-20(26)14-4-2-3-5-17(14)25(27)28/h2-7,12-13,21H,8-11H2,1H3,(H,22,23,26)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
64n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50130459
PNG
(CHEMBL321343 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3[N+]([O-])=O)nc12
Show InChI InChI=1S/C20H21N5O3/c1-24-10-8-13(9-11-24)15-12-21-16-6-7-18(22-19(15)16)23-20(26)14-4-2-3-5-17(14)25(27)28/h2-7,12-13,21H,8-11H2,1H3,(H,22,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
170n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair