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BDBM50130460 CHEMBL316979::N-[3-(1-Ethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-4-fluoro-benzamide

SMILES: CCN1CCC(=CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12

InChI Key: InChIKey=KKMBLUZZKPJQGN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130460   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130460
PNG
(CHEMBL316979 | N-[3-(1-Ethyl-1,2,3,6-tetrahydro-py...)
Show SMILES CCN1CCC(=CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12
Show InChI InChI=1S/C21H21FN4O/c1-2-26-11-9-14(10-12-26)17-13-23-18-7-8-19(24-20(17)18)25-21(27)15-3-5-16(22)6-4-15/h3-9,13,23H,2,10-12H2,1H3,(H,24,25,27)
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Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair