BDBM50130757 CHEMBL3634516

SMILES [H][C@]12CCC[C@H](N3CCCC3)[C@@]1([H])N(CCN2C(=O)OC)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PAVYSOUZQLFNIW-IRFCIJBXSA-N

Data  7 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50130757   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]U-69,593 from kappa-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]U-69,593 from KOR in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  43nMAssay Description:Inhibitory activity towards Alpha-mannosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-DPDPE from delta opioid receptor in rat brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]DPDPE from DOR in Sprague-Dawley rat brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataEC50:  2nMAssay Description:Agonist activity at recombinant human kappa-type opioid receptor expressed in HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Dr. August Wolff Gmbh & Co. Kg Arzneimittel

Curated by ChEMBL
LigandPNGBDBM50130757(CHEMBL3634516)
Affinity DataEC50:  2nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed