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BDBM50131129 2-(4-Methyl-pyridin-2-ylamino)-benzothiazole-6-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL86592

SMILES: Cc1ccnc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cc(C)cc2C)c1

InChI Key: InChIKey=UORALWJDAKMZIC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131129   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SRC


(Homo sapiens (human))
BDBM50131129
PNG
(2-(4-Methyl-pyridin-2-ylamino)-benzothiazole-6-car...)
Show SMILES Cc1ccnc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cc(C)cc2C)c1
Show InChI InChI=1S/C23H22N4OS/c1-13-7-8-24-20(11-13)26-23-25-18-6-5-17(12-19(18)29-23)22(28)27-21-15(3)9-14(2)10-16(21)4/h5-12H,1-4H3,(H,27,28)(H,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 32n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human p56 Lck tyrosine kinase


Citation and Details
More data for this
Ligand-Target Pair