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BDBM50131130 2-(2H-Pyridazin-1-ylamino)-benzothiazole-6-carboxylic acid (2-chloro-6 -methyl-phenyl)-amide::CHEMBL315279

SMILES: Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NN3C=CCC=N3)sc2c1

InChI Key: InChIKey=UFCRFKKFIGKAAR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131130   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SRC


(Homo sapiens (Human))
BDBM50131130
PNG
(2-(2H-Pyridazin-1-ylamino)-benzothiazole-6-carboxy...)
Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NN3C=CCC=N3)sc2c1
Show InChI InChI=1S/C19H16ClN5OS/c1-12-5-4-6-14(20)17(12)23-18(26)13-7-8-15-16(11-13)27-19(22-15)24-25-10-3-2-9-21-25/h3-11H,2H2,1H3,(H,22,24)(H,23,26)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 41n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human p56 Lck tyrosine kinase


Bioorg Med Chem Lett 13: 2587-90 (2003)


Article DOI: 10.1016/s0960-894x(03)00511-0
BindingDB Entry DOI: 10.7270/Q2FX78V4
More data for this
Ligand-Target Pair