BDBM50131579 4-[4-Chloro-5-(4-ethoxy-phenyl)-imidazol-1-yl]-benzenesulfonamide::CHEMBL324312

SMILES CCOc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=SWGSPVCVQPOXFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131579   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131579(4-[4-Chloro-5-(4-ethoxy-phenyl)-imidazol-1-yl]-ben...)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131579(4-[4-Chloro-5-(4-ethoxy-phenyl)-imidazol-1-yl]-ben...)
Affinity DataIC50:  27nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131579(4-[4-Chloro-5-(4-ethoxy-phenyl)-imidazol-1-yl]-ben...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2) in 143982 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed