BDBM50131591 4-Chloro-5-(3-chloro-4-ethoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole::CHEMBL327150

SMILES CCOc1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=NZESAJWMQSEBNZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131591   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131591(4-Chloro-5-(3-chloro-4-ethoxy-phenyl)-1-(4-methane...)
Affinity DataIC50:  7nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131591(4-Chloro-5-(3-chloro-4-ethoxy-phenyl)-1-(4-methane...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed