BDBM50131607 CHEMBL333505::{3-[5-Chloro-3-(4-methanesulfonyl-phenyl)-3H-imidazol-4-yl]-pyridin-4-yl}-diethyl-amine

SMILES CCN(CC)c1ccncc1-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=ISAYKCYNWCTUIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131607   

TargetProstaglandin G/H synthase 2(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131607({3-[5-Chloro-3-(4-methanesulfonyl-phenyl)-3H-imida...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131607({3-[5-Chloro-3-(4-methanesulfonyl-phenyl)-3H-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed