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BDBM50132143 CHEMBL3633720

SMILES: C[C@H](NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1

InChI Key: InChIKey=MWDVCHRYCKXEBY-LBPRGKRZSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132143   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 139


(Homo sapiens)
BDBM50132143
PNG
(CHEMBL3633720)
Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1
Show InChI InChI=1S/C17H17ClN2O2/c1-12(13-6-3-2-4-7-13)20-16(21)11-19-17(22)14-8-5-9-15(18)10-14/h2-10,12H,11H2,1H3,(H,19,22)(H,20,21)/t12-/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Janssen Research& Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1


ACS Med Chem Lett 6: 1015-8 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00247
BindingDB Entry DOI: 10.7270/Q2RX9DWS
More data for this
Ligand-Target Pair