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BDBM50132366 2-(4'-Hydroxy-biphenyl-3-yl)-6-morpholin-4-yl-thiopyran-4-one::CHEMBL104450

SMILES: Oc1ccc(cc1)-c1cccc(c1)-c1cc(=O)cc(s1)N1CCOCC1

InChI Key: InChIKey=RIMUFIAYXCMUTQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132366   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-dependent protein kinase


(Homo sapiens (Human))
BDBM50132366
PNG
(2-(4'-Hydroxy-biphenyl-3-yl)-6-morpholin-4-yl-thio...)
Show SMILES Oc1ccc(cc1)-c1cccc(c1)-c1cc(=O)cc(s1)N1CCOCC1
Show InChI InChI=1S/C21H19NO3S/c23-18-6-4-15(5-7-18)16-2-1-3-17(12-16)20-13-19(24)14-21(26-20)22-8-10-25-11-9-22/h1-7,12-14,23H,8-11H2
PDB

KEGG

DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 350n/an/an/an/an/an/a



University of Newcastle

Curated by ChEMBL


Assay Description
In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.


Bioorg Med Chem Lett 13: 3083-6 (2003)


Article DOI: 10.1016/s0960-894x(03)00652-8
BindingDB Entry DOI: 10.7270/Q2WS8SP4
More data for this
Ligand-Target Pair